Modelling extracellular electrical stimulation: part 4. Effect of the cellular composition of neural tissue on its spatio-temporal filtering properties
B Tahayori, H Meffin, EN Sergeev, IMY Mareels, AN Burkitt, DB Grayden
Journal of Neural Engineering | IOP Publishing | Published : 2014
Objective. The objective of this paper is to present a concrete application of the cellular composite model for calculating the membrane potential, described in an accompanying paper. Approach. A composite model that is used to determine the membrane potential for both longitudinal and transverse modes of stimulation is demonstrated. Main results. Two extreme limits of the model, near-field and far-field for an electrode close to or distant from a neuron, respectively, are derived in this paper. Results for typical neural tissue are compared using the composite, near-field and far-field models as well as the standard isotropic volume conductor model. The self-consistency of the composite mod..View full abstract
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Awarded by Australian Research Council (ARC) through its Special Research Initiative (SRI) in Bionic Vision Science and Technology grant
Awarded by Victorian Life Sciences Computation Initiative (VLSCI)
This research was supported by the Australian Research Council (ARC) through its Special Research Initiative (SRI) in Bionic Vision Science and Technology grant to Bionic Vision Australia (BVA) 10.13039/501100000923: SR1000005. The Bionics Institute acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program. This research was supported by a Victorian Life Sciences Computation Initiative (VLSCI) grant number VR0138 on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government.