Journal article
Exposure to parental smoking in Childhood or adolescence is associated with increased carotid intima-media thickness in young adults: Evidence from the Cardiovascular Risk in Young Finns study and the Childhood Determinants of Adult Health study
S Gall, QL Huynh, CG Magnussen, M Juonala, JSA Viikari, M Kähönen, T Dwyer, OT Raitakari, A Venn
European Heart Journal | Published : 2014
Abstract
Aim: Recent evidence suggests that the exposure of children to their parents' smoking adversely effects endothelial function in adulthood. We investigated whether the association was also present with carotid intima-media thickness (IMT) up to 25 years later. Methods and results: The study comprised participants from the Cardiovascular Risk in Young Finns Study (YFS,n = 2401) and the Childhood Determinants of Adult Health (CDAH,n = 1375) study. Exposuretoparental smoking(none,one, or both) wasassessed at baseline by questionnaire. B-mode ultrasound of the carotid artery determined IMT in adulthood. Linear regression on a pooled dataset accounting for the hierarchical data and potential confo..
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Awarded by Commonwealth Scholarship Commission
Funding Acknowledgements
The Childhood Determinants of Adult Health study was supported at baseline by the Commonwealth Departments of Sport, Recreation and Tourism, and Health; the National Heart Foundation; and the Commonwealth Schools Commission and at follow-up by the National Health and Medical Research Council, the Heart Foundation, the Tasmanian Community Fund, and Veolia Environmental Services. S.L.G. is supported by a National Heart Foundation of Australia post-doctoral fellowship. C. G. M. is supported by a National Health and Medical Research Council Early Career Fellowship. A.V. is supported by a National Health and Medical Research Council Career Development Fellowship. The Young Finns Study has been financially supported by the Academy of Finland: grants 134309 (Eye), 126925, 121584, 124282, 129378 (Salve), 117787 (Gendi), and 41071 (Skidi), the Social Insurance Institution of Finland, Kuopio, Tampere and Turku University Hospital Medical Funds, Juho Vainio Foundation, Paavo Nurmi Foundation, Finnish Foundation of Cardiovascular Research and Finnish Cultural Foundation, Tampere Tuberculosis Foundation and Emil Aaltonen Foundation.