Trends Over Time in the Risk of Stroke After an Incident Transient Ischemic Attack
Vijaya Sundararajan, Amanda G Thrift, Thanh G Phan, Philip M Choi, Ben Clissold, Velandai K Srikanth
Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2014
BACKGROUND AND PURPOSE: Long-term population trends in the early risk of stroke after transient ischemic attack (TIA) are unknown. We hypothesized that there has been an appreciable decline in the risk of stroke after TIA for the last decade. METHODS: Population-level cohort study from Victoria, Australia (population 5.6 million), using linked data from hospitals, emergency departments, and death records (2001-2011), with a 2-year clearance period to define incident TIAs. Age-specific rates/1000, yearly incident rate ratios, and age-sex-adjusted risk of stroke after TIA were computed. RESULTS: The mean age of 46 971 patients with TIA was 71 (SD=15), 52% women. In patients ≥65 years, annual T..View full abstract
Awarded by National Health and Medical Research Council
The project received funding from a Pfizer Australia Cardiovascular Lipid Research Grant, 2010. V. K. Srikanth is the recipient of a National Health and Medical Research Foundation of Australia/National Heart Foundation Career Development Fellowship. A. G. Thrift was supported by a Senior Research Fellowship from the National Health and Medical Research Council (1042600).