Journal article
Evolution of practice during the interventional management of stroke III trial and implications for ongoing trials
JP Broderick, YY Palesch, AM Demchuk, SD Yeatts, P Khatri, MD Hill, EC Jauch, TG Jovin, B Yan, R Von Kummer, CA Molina, M Goyal, M Mazighi, WJ Schonewille, ST Engelter, C Anderson, J Spilker, J Carrozzella, LS Janis, LD Foster Show all
Stroke | Published : 2014
Abstract
Background and Purpose - We explored changes in the patient population and practice of endovascular therapy during the course of the Interventional Management of Stroke (IMS) III Trial.Methods - Changes in baseline characteristics, use of baseline CT angiography, treatment times and specifics, and outcomes were compared between the first 4 protocols and the fifth and final protocol.Results - Compared with subjects treated in the first 4 protocol versions (n=610), subjects treated in fifth and final protocol (n=46) were older (75 versus 68 years, P<0.0002) and less likely to have a pretreatment Rankin of 0 (76% versus 89%, P=0.01), were more likely to have a pretreatment CT angiography (65% v..
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Awarded by National Institute of Neurological Disorders and Stroke