Journal article
Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions
AC Kotze, PW Hunt, P Skuce, G von Samson-Himmelstjerna, RJ Martin, H Sager, J Krücken, J Hodgkinson, A Lespine, AR Jex, JS Gilleard, RN Beech, AJ Wolstenholme, J Demeler, AP Robertson, CL Charvet, C Neveu, R Kaminsky, L Rufener, M Alberich Show all
International Journal for Parasitology Drugs and Drug Resistance | Published : 2014
Abstract
Anthelmintic resistance has a great impact on livestock production systems worldwide, is an emerging concern in companion animal medicine, and represents a threat to our ongoing ability to control human soil-transmitted helminths. The Consortium for Anthelmintic Resistance and Susceptibility (CARS) provides a forum for scientists to meet and discuss the latest developments in the search for molecular markers of anthelmintic resistance. Such markers are important for detecting drug resistant worm populations, and indicating the likely impact of the resistance on drug efficacy. The molecular basis of resistance is also important for understanding how anthelmintics work, and how drug resistant ..
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Awarded by European Commission
Funding Acknowledgements
Funds to support the CARS2013 meeting were provided by Zoetis, and Virbac Animal Health. Alessandro Puoti is thanked for providing Figs. 4A and B. Support to RJM was via NIH grant R01 AI047194 National Institute of Allergy and Infectious Diseases. The funding agency had no role in the design, execution or publication of these studies. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Allergy and Infectious Diseases.