Journal article

Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation

Rajeev K Pathak, Melissa E Middeldorp, Dennis H Lau, Abhinav B Mehta, Rajiv Mahajan, Darragh Twomey, Muayad Alasady, Lorraine Hanley, Nicholas A Antic, R Doug McEvoy, Jonathan M Kalman, Walter P Abhayaratna, Prashanthan Sanders

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | ELSEVIER SCIENCE INC | Published : 2014

Abstract

BACKGROUND: The long-term outcome of atrial fibrillation (AF) ablation demonstrates attrition. This outcome may be due to failure to attenuate the progressive substrate promoted by cardiovascular risk factors. OBJECTIVES: The goal of this study was to evaluate the impact of risk factor and weight management on AF ablation outcomes. METHODS: Of 281 consecutive patients undergoing AF ablation, 149 with a body mass index ≥27 kg/m(2) and ≥1 cardiac risk factor were offered risk factor management (RFM) according to American Heart Association/American College of Cardiology guidelines. After AF ablation, all 61 patients who opted for RFM and 88 control subjects were assessed every 3 to 6 months by ..

View full abstract