Journal article

The relationship between porosity and specific surface in human cortical bone is subject specific

C Lerebours, CDL Thomas, JG Clement, PR Buenzli, P Pivonka

Bone | Published : 2015

Abstract

A characteristic relationship for bone between bone volume fraction (BV/TV) and specific surface (BS/TV) has previously been proposed based on 2D histological measurements. This relationship has been suggested to be bone intrinsic, i.e., to not depend on bone type, bone site and health state. In these studies, only limited data comes from cortical bone. The aim of this paper was to investigate the relationship between BV/TV and BS/TV in human cortical bone using high-resolution micro-CT imaging and the correlations with subject-specific biometric data such as height, weight, age and sex. Images from femoral cortical bone samples of the Melbourne Femur Collection were obtained using synchrotr..

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University of Melbourne Researchers

Grants

Awarded by Access to Major Research Facilities Programme, International Science Linkages Programme


Funding Acknowledgements

Financial support for the work in Japan came from the Access to Major Research Facilities Programme, 07/08-S-21, which is a component of the International Science Linkages Programme established under the Australian Government's innovation statement, "Backing Australia's Ability" and from the Faculty of Medicine, Dentistry and Health Sciences of the University of Melbourne. At SPring8 Dr Kentaro Uesugi (Beamline Scientist, beamline 20B2) and Dr Naoto Yagi (Chief Biological Scientist) gave great assistance and encouragement.