Capture of Somatic mtDNA Point Mutations with Severe Effects on Oxidative Phosphorylation in Synaptosome Cybrid Clones from Human Brain

Matthew McKenzie; Maria Chiotis; Jana Hroudova; Maria IG Lopez Sanchez; Sze Chern Lim; Mark J Cook; Penny McKelvie; Richard GH Cotton; Michael Murphy; Justin C St John; Ian A Trounce

Journal article

Capture of Somatic mtDNA Point Mutations with Severe Effects on Oxidative Phosphorylation in Synaptosome Cybrid Clones from Human Brain

Matthew McKenzie, Maria Chiotis, Jana Hroudova, Maria IG Lopez Sanchez, Sze Chern Lim, Mark J Cook, Penny McKelvie, Richard GH Cotton, Michael Murphy, Justin C St John, Ian A Trounce

Human Mutation | WILEY-BLACKWELL | Published : 2014

DOI: 10.1002/humu.22694

University of Melbourne Researchers

Penelope McKelvie Author Clinical Pathology

Ian Trounce Author Melbourne Medical School

Michael Murphy Author Surgery - St Vincent's Hospital

Mark Cook Author

Isabel Lopez Sanchez Author Ophthalmology Eye and Ear Hospital

Grants

Awarded by Australian National Health and Medical Research Council

Awarded by Czech Republic

Funding Acknowledgements

Contract grant sponsor: Poxon Neurosurgical Foundation; the Australian National Health and Medical Research Council (APP1061472); Wagstaff Bequest of the Royal Victorian Eye and Ear Hospital; Australian Research Council Future Fellowship Scheme; William Buckland Foundation; Monash University; MIMR-PHI; Group of Eight Fellowship and Czech Republic award PRVOUK-P26/LF1/4; Victorian Government Infrastructure Program.