Journal article

Serum Inhibin B Values in Boys with Unilateral Vanished Testis or Unilateral Cryptorchidism

Jorgen Thorup, Kolja Kvist, Erik Clasen-Linde, John M Hutson, Dina Cortes

JOURNAL OF UROLOGY | ELSEVIER SCIENCE INC | Published : 2015

Abstract

PURPOSE: Boys with cryptorchidism have overall increased gonadotropin and decreased serum inhibin B levels compared to normal. Serum inhibin B levels, produced by Sertoli cells, may reflect the state of germinative epithelium in cryptorchid testes. We evaluated whether serum inhibin B levels differed between boys with unilateral vanished testis and those with unilateral cryptorchidism. MATERIALS AND METHODS: Blood samples from 297 boys 1.5 to 5 years old were included, of whom 222 had unilateral cryptorchidism, 29 had unilateral vanished testis and 46 had undergone unilateral orchiopexy 1 year previously. Serum inhibin B levels were measured using a commercially available ELISA kit and were ..

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