Journal article
Febrile seizures following measles and varicella vaccines in young children in Australia
KK Macartney, HF Gidding, L Trinh, H Wang, J McRae, N Crawford, M Gold, A Kynaston, C Blyth, Z Yvonne, E Elliott, R Booy, J Buttery, H Marshall, M Nissen, P Richmond, PB McInytre, N Wood
Vaccine | ELSEVIER SCI LTD | Published : 2014
Abstract
BACKGROUND: Febrile seizures (FS) are common in childhood with incidence peaking in the second year of life when measles and varicella-containing vaccines are administered. This study aimed to examine the vaccine-attributable risk of FS following separate administration of MMR and monovalent varicella vaccines (VV) prior to a planned change to MMRV as the second dose of measles-containing vaccine at 18 months of age. METHODS: All FS cases in children aged <5 years from 1st January 2012 to 30th April 2013 were identified from emergency department (ED) and inpatient databases at five Australian tertiary paediatric hospitals participating in PAEDS (Paediatric Active Enhanced Disease Surveillanc..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This study was conducted using funding from Australian Government Department of Health and the participating State's Departments of Health (New South Wales, Western Australia, South Australia, Victoria and Queensland). Funding to assist in the conduct of this study was also obtained from the Australian National Health and Medical Research Council (NHRMC) project grant number: 1049557.