Journal article

Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors

Huiling Xu, Yuqian Yan, Siddhartha Deb, Danny Rangasamy, Markus Germann, Jordane Malaterre, Noreen C Eder, Robyn L Ward, Nicholas J Hawkins, Richard W Tothill, Long Chen, Neil J Mortensen, Stephen B Fox, Michael J McKay, Robert G Ramsay

Cell Reports | CELL PRESS | Published : 2014

DOI: 10.1016/j.celrep.2014.10.059

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Keywords

Cell Biology
Adult Stem Cells
Stem-Cells
Poor-Prognosis
Cell Proliferation
Retroelements
Dna-Damage
Chromosomal Instability
Chromosome Cohesion
Dna-Binding Proteins
Homologous Recombination
Gene-Expression
Dna Damage
Phosphoproteins
Vertebrate Cells
Haploinsufficiency
Adenomatous Polyposis Coli
Science & Technology
Adenomatous Polyposis
Mice
Cell Cycle Proteins
Apc Mutations
Gene Expression
Humans
Gene Expression Regulation, Neoplastic
Colon
Chromatin Architecture
Mice, Transgenic
Hct116 Cells
Nuclear Proteins
Life Sciences & Biomedicine
Animals
Up-Regulation