Journal article

Resting state functional connectivity changes induced by prior brain state are not network specific

Chris Tailby, Richard AJ Masterton, Jenny Y Huang, Graeme D Jackson, David F Abbott



Resting state functional connectivity (rFC) is used to identify functionally related brain areas without requiring subjects to perform specific tasks. Previous work suggests that prior brain state, as determined by the activity engaged in immediately prior to collection of resting state data, can influence the networks recovered by rFC analyses. We determined the prevalence and network specificity of rFC changes induced by manipulations of prior state (including an unstructured (unconstrained) state, and language and motor tasks). Three blocks of rest data (one after each of the specified prior states) were acquired on each of 25 subjects. We hypothesised that prior state induced changes in ..

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Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

We thank Anthony B. Waites and Alexandra Stanislavsky for assistance with data collection. This study was supported by the National Health and Medical Research Council of Australia (Programme Grant 628952 and practitioner fellowship 527800 to GDJ), the Austin Hospital Medical Research Foundation and the Operational Infrastructure Support Program of the State Government of Victoria, Australia.