Journal article

Disrupted Functional Connectivity in Dorsal and Ventral Attention Networks During Attention Orienting in Autism Spectrum Disorders

Jacqueline Fitzgerald, Katherine Johnson, Elizabeth Kehoe, Arun LW Bokde, Hugh Garavan, Louise Gallagher, Jane McGrath

Autism Research | WILEY | Published : 2015

Abstract

BACKGROUND: Attention orienting is a cognitive process that facilitates the movement of attention focus from one location to another: this may be impaired in autism spectrum disorder (ASD). Dorsal and ventral attention networks (DAN and VAN) sub-serve the process of attention orienting. This study investigated the functional connectivity of attention orienting in these networks in ASD using the Posner Cueing Task. METHOD: Twenty-one adolescents with ASD and 21 age and IQ matched controls underwent functional magnetic resonance imaging. A psychophysical interaction (PPI) analysis was implemented to investigate task-dependent functional connectivity, measuring synchronicity of brain regions du..

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