Nasality in Friedreich ataxia
Matthew L Poole, Jessica S Wee, Joanne E Folker, Louise A Corben, Martin B Delatycki, Adam P Vogel
CLINICAL LINGUISTICS & PHONETICS | INFORMA HEALTHCARE | Published : 2015
Perceptual speech research in Friedreich ataxia (FRDA) has identified altered nasality as a key component of the dysarthria profile, however the incidence and severity of abnormal nasality remains unknown. Utilizing objective and perceptual methods, data on the relationship between resonance, disease duration, severity, age of onset and genetic profiles were collated. Thirty-seven participants with FRDA and 24 healthy controls provided contemporaneous speech samples for perceptual analysis, and single word samples for acoustic analysis. A subset of participants (eight participants with FRDA and eight controls) underwent nasometry assessment. Twenty-seven participants with FRDA presented with..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC) Early Career Research Fellowships
The authors report no declarations of interest. APV and LAC hold National Health and Medical Research Council (NHMRC) Early Career Research Fellowships (ID1012302 & ID1037002 respectively).