Journal article

Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

Conan K Wang, Susan E Northfield, Barbara Colless, Stephanie Chaousis, Ingrid Hamernig, Rink-Jan Lohman, Daniel S Nielsen, Christina I Schroeder, Spiros Liras, David A Price, David P Fairlie, David J Craik

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2014

Grants

Awarded by Australian Research Council Linkage Grant


Awarded by National Health and Medical Research Council (NHMRC) Early Career Research Fellowship


Funding Acknowledgements

We thank Olivier Cheneval and Phillip Walsh for help with peptide synthesis. Caco-2 cells were kindly provided by Prof. Istvan Toth. This work was supported by Australian Research Council Linkage Grant LP110200213, co-funded by Pfizer and a Queensland Government Smart Futures Co-investment Grant. C.K.W. was supported by a National Health and Medical Research Council (NHMRC) Early Career Research Fellowship (546578). D.P.F. and D.J.C. are NHMRC Senior Principal Research Fellows (APP1027369, APP1026501).