Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1

Carol M Taylor; Susan E Northfield; Conan K Wang; David J Craik

Journal article

Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1

Carol M Taylor, Susan E Northfield, Conan K Wang, David J Craik

Tetrahedron | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2014

DOI: 10.1016/j.tet.2014.06.058

University of Melbourne Researchers

Susan Northfield Author Pharmacology and Therapeutics

Grants

Awarded by ARC Linkage Grant

Funding Acknowledgements

We thank Phillip Walsh and Olivier Cheneval for help with peptide synthesis, isolation, and purification. This work was supported by an ARC Linkage Grant (LP110200213). C.K.W. is a National Health and Medical Research Council Early Career Research Fellow (546578). D.J.C. is a National Health and Medical Research Council Professorial Fellow (APP1026501). C.M.T. thanks Louisiana State University for a sabbatical leave and D.J.C. for the opportunity to spend that time in his laboratory.