Enhanced Structure-Function Relationship in Glaucoma With an Anatomically and Geometrically Accurate Neuroretinal Rim Measurement
Vishva M Danthurebandara, Glen P Sharpe, Donna M Hutchison, Jonathan Denniss, Marcelo T Nicolela, Allison M McKendrick, Andrew Turpin, Balwantray C Chauhan
Investigative Ophthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2015
PURPOSE: To evaluate the structure-function relationship between disc margin-based rim area (DM-RA) obtained with confocal scanning laser tomography (CSLT), Bruch's membrane opening-based horizontal rim width (BMO-HRW), minimum rim width (BMO-MRW), peripapillary retinal nerve fiber layer thickness (RNFLT) obtained with spectral-domain optical coherence tomography (SD-OCT), and visual field sensitivity. METHODS: We examined 151 glaucoma patients with CSLT, SD-OCT, and standard automated perimetry on the same day. Optic nerve head (ONH) and RNFL with SD-OCT were acquired relative to a fixed coordinate system (acquired image frame [AIF]) and to the eye-specific fovea-BMO center (FoBMO) axis. Vi..View full abstract
Awarded by Canadian Institutes of Health Research, Ottawa, Ontario
Awarded by Australian Research Council
Supported by Grants MOP11357 (BCC) from the Canadian Institutes of Health Research, Ottawa, Ontario; unrestricted research support from Heidelberg Engineering (BCC), Heidelberg, Germany; and Grant LP130100055 from the Australian Research Council (AMM, AT).