Journal article

Microperimetry of nascent geographic atrophy in age-related macular degeneration

Z Wu, LN Ayton, CD Luu, RH Guymer

Investigative Ophthalmology and Visual Science | Published : 2014

Abstract

PURPOSE. To determine the microperimetric retinal sensitivity in areas with nascent geographic atrophy (nGA) compared with other pathological features in eyes with intermediate AMD.METHODS. Participants with bilateral intermediate AMD underwent microperimetry examinations and high-resolution spectral-domain optical coherence tomography (SD-OCT) scans in a prospective study. Twenty-two participants (24 eyes) identified as having a microperimetric stimulus sampling an atrophic area (nGA or drusen-associated atrophy detected on SD-OCT) in an eye were analyzed, using three neighboring nonatrophic regions (with or without AMDassociated features) in the same eye as reference areas.RESULTS. On aver..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC


Awarded by University of Melbourne


Awarded by NH&MRC Centre for Clinical Research Excellence


Funding Acknowledgements

Supported by the National Health and Medical Research Council (NH&MRC) Project Grant (1027624); NH&MRC Practitioner Fellowship (RHG, #529905); Macular Disease Foundation Australia (MDFA) Research Grant; Bupa Health Foundation (Australia); The Menzies Foundation; a University of Melbourne Early Career Research grant (LNA, #1350114); and the Macular Vision Loss Support Society of Australia, Inc. CERA receives Operational Infrastructure Support from the Victorian Government and is supported by a NH&MRC Centre for Clinical Research Excellence award (#529923).