Conference Proceedings
Effect of gender and diabetes on major depressive disorder using heart rate asymmetry
CK Karmakar, HF Jelinek, P Warner, AH Khandoker, M Palaniswami
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE | IEEE Press | Published : 2014
Abstract
In this study, we have investigated how heart rate asymmetry (HRA) changes in major depressive disorder (MDD) subjects with comorbid diabetes as well as in male and female. Depression score was determined based on PHQ-9 questionnaire and from 135 subjects 70 subjects were selected with 1000 or more RR intervals. Heart rate asymmetry is a Poincaré plot based nonlinear technique to analyze the asymmetry using RR interval time-series signal. Three commonly used HRA indices Guzik's index (GI), Porta's index (PI) and Ehlers' index (EI) were used to understand the changes in HRA in MDD. Results indicate significantly (p < ;0.05) different GI and EI values between 'Dep' and 'NonDep' subgroups in 'C..
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