Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways
Jessica M Haverkamp, Amber M Smith, Ricardo Weinlich, Christopher P Dillon, Joseph E Qualls, Geoffrey Neale, Brian Koss, Young Kim, Vincenzo Bronte, Marco J Herold, Douglas R Green, Joseph T Opferman, Peter J Murray
Immunity | CELL PRESS | Published : 2014
Awarded by NHMRC
Awarded by NIH Cancer Center
We thank R. Pope (Northwestern University) for the gift of the c-FLIP knockout mice and R. Cross and his team for cell sorting and J. Wu and S. Mao for the statistical analysis of tumor formation in TH-MYCN MCL-1 Delta M mice and B. Blazar for discussions. This work was supported by NIH Cancer Center developmental funds (P.J.M. and J.T.O.), The Hartwell Foundation Individual Biomedical Research Award (P.J.M.), Alex's Lemonade Stand Foundation (P.J.M.), NHMRC project grant APP1049720 (M.J.H.), NIH Cancer Center grant P30 CA21765, and the American Lebanese Syrian Associated Charities.