A selective involvement of putamen functional connectivity in youth with internet gaming disorder
Soon-Beom Hong, Ben J Harrison, Orwa Dandash, Eun-Jung Choi, Seong-Chan Kim, Ho-Hyun Kim, Do-Hyun Shim, Chang-Dai Kim, Jae-Won Kim, Soon-Hyung Yi
Brain Research | ELSEVIER SCIENCE BV | Published : 2015
Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Among twelve right-handed male adolescents with internet gaming disorder and 11 right-handed and gender-matched healthy controls, we examined group differences in the functional connectivity of dorsal and ventral subdivisions of the caudate nucleus and putamen, as well as the association of these connectivity indices with behavioral measures of internet use. Adolescents with interne..View full abstract
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Awarded by National Health and Medical Research Council of Australia (NHMRC) Clinical Career Development Award
This work was supported by the Seoul National University Brain Fusion Program Research Fund. S.-B. Hong was supported by a National Research Foundation of Korea (NRF) Grant (Global Internship Program) funded by the Korean government (MEST). B.J. Harrison is supported by a National Health and Medical Research Council of Australia (NHMRC) Clinical Career Development Award (I.D. 628509). The funders had no role in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the paper for publication. No potential conflict of interest relevant to this article was reported.