Journal article

The Emergence of Age-Dependent Social Cognitive Deficits After Generalized Insult to the Developing Brain: A Longitudinal Prospective Analysis Using Susceptibility-Weighted Imaging

Nicholas P Ryan, Cathy Catroppa, Janine M Cooper, Richard Beare, Michael Ditchfield, Lee Coleman, Timothy Silk, Louise Crossley, Miriam H Beauchamp, Vicki A Anderson

Human Brain Mapping | WILEY | Published : 2015

Abstract

Childhood and adolescence are critical periods for maturation of neurobiological processes that underlie complex social and emotional behavior including Theory of Mind (ToM). While structural correlates of ToM are well described in adults, less is known about the anatomical regions subsuming these skills in the developing brain or the impact of cerebral insult on the acquisition and establishment of high-level social cognitive skills. This study aimed to examine the differential influence of age-at-insult and brain pathology on ToM in a sample of children and adolescents with traumatic brain injury (TBI). Children and adolescents with TBI (n = 112) were categorized according to timing of bra..

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