The Emergence of Age-Dependent Social Cognitive Deficits After Generalized Insult to the Developing Brain: A Longitudinal Prospective Analysis Using Susceptibility-Weighted Imaging
Nicholas P Ryan, Cathy Catroppa, Janine M Cooper, Richard Beare, Michael Ditchfield, Lee Coleman, Timothy Silk, Louise Crossley, Miriam H Beauchamp, Vicki A Anderson
Human Brain Mapping | WILEY | Published : 2015
Childhood and adolescence are critical periods for maturation of neurobiological processes that underlie complex social and emotional behavior including Theory of Mind (ToM). While structural correlates of ToM are well described in adults, less is known about the anatomical regions subsuming these skills in the developing brain or the impact of cerebral insult on the acquisition and establishment of high-level social cognitive skills. This study aimed to examine the differential influence of age-at-insult and brain pathology on ToM in a sample of children and adolescents with traumatic brain injury (TBI). Children and adolescents with TBI (n = 112) were categorized according to timing of bra..View full abstract
This work was supported by a grant from the Victoria Neurotrauma Initiative, Australia and the Victorian Government Operational Infrastructure Support Program. The funding bodies did not play a role in the design of the study, collection, analysis and interpretation of the data, or writing of the manuscript.