Dosimetric factors associated with weight loss during (chemo)radiotherapy treatment for lung cancer

N Kiss; M Krishnasamy; S Everitt; K Gough; M Duffy; E Isenring

Journal article

Dosimetric factors associated with weight loss during (chemo)radiotherapy treatment for lung cancer

N Kiss, M Krishnasamy, S Everitt, K Gough, M Duffy, E Isenring

EUROPEAN JOURNAL OF CLINICAL NUTRITION | NATURE PUBLISHING GROUP | Published : 2014

DOI: 10.1038/ejcn.2014.166

Abstract

Background/Objectives:Thoracic radiotherapy (RT) is associated with acute toxicities, including oesophagitis, which can have an impact on nutritional intake and subsequently lead to malnutrition. This study aimed to identify RT dosimetric factors associated with ≥5% weight loss in patients receiving treatment for non-small-cell lung cancer (NSCLC).Methods:Radiation dose data to the oesophagus (including mean, maximum dose and oesophageal length) were retrospectively analysed for a cohort of 54 NSCLC patients treated with concurrent chemoradiotherapy between 2004 and 2006. Weight change was calculated using the lowest weight during the 90 days from RT commencement compared with the start of R..

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University of Melbourne Researchers

Sarah Everitt Author The Sir Peter Maccallum Department of Oncology

Karla Gough Author Nursing

Meinir Krishnasamy Author The Sir Peter Maccallum Department of Oncology

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Funding Acknowledgements

We acknowledge the contributions of D Ball, M Bressel and C Russell in the design and collection of data for the original study. This study was supported by a PhD scholarship from the Victorian Cancer Agency.