Journal article
Anxiety and depression symptoms in the 2 years following diagnosis of breast or gynaecologic cancer: prevalence, course and determinants of outcome
L Stafford, F Judd, P Gibson, A Komiti, GB Mann, M Quinn
Supportive Care in Cancer | Published : 2015
Abstract
Purpose: The purposes of this study are to examine the course and prevalence of anxiety and depression over 24 months in women with newly diagnosed breast and gynaecologic cancer and, controlling for demographic and clinical confounders, to test the role of neuroticism and psychiatric history in determining outcome 6, 12, 18 and 24 months post-diagnosis. Methods: Participants completed the Hospital Anxiety and Depression Scale—anxiety subscale and Centre for Epidemiological Studies Depression Scale on an 8-weekly basis from diagnosis until 96 weeks. Changes over time were analyzed with repeated measures ANOVA. Hierarchical linear regression, adjusted a priori for age, chemotherapy and radiat..
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Funding Acknowledgements
This study was supported in part by funding from the Western and Central Melbourne Integrated Cancer Service (WCMICS). The Centre for Women's Mental Health is supported by the Pratt Foundation. The funding sources had no role in the study design, or collection, analysis and interpretation of data or in the decision to submit the work for publication. The authors wish to thank the breast care nurses Robyn Cordner, Monique Baldacchino, Kerry Shanahan, Bronwyn Flanagan and Claire Noonan for their assistance in recruiting patients to the study. Dr Chad Bousman is acknowledged for his statistical advice. We also thank the participating patients for their support of this research.