Impact of Blood Pressure on Retinal Microvasculature Architecture Across the Lifespan: The Young Finns Study
Robyn J Tapp, S Monira Hussain, Josephine Battista, Nina Hutri-Kahonen, Terho Lehtimaki, Alun D Hughes, Simon A McG Thom, Andrew Metha, Olli T Raitakari, Mika Kahonen
Microcirculation | WILEY | Published : 2015
OBJECTIVE: The present study examined the impact of BP from childhood to mid-adulthood on retinal microvascular architecture. METHODS: The Cardiovascular Risk in Young Finns Study included children aged 3-18 years, from five Finnish University cities, with participants chosen randomly from the national population registrar from those areas. The age of participants included in the current analyses in childhood (1980) ranged from three to nine years and in mid-adulthood (2011) ranged from 34 to 40 years (complete data n = 657). Measures of retinal microvasculature architecture measured in adulthood included diameters, tortuosity, lengths, and LDR. RESULTS: Regression analysis showed a strong n..View full abstract
Awarded by Academy of Finland
Awarded by British Heart Foundation
The Young Finns Study has been financially supported by the Academy of Finland: grants 134309 (Eye), 126925, 121584, 124282, 129378 (Salve), 117797 (Gendi), and 41071 (Skidi), the Social Insurance Institution of Finland, Kuopio, Tampere and Turku University Hospital Medical Funds, Juho Vainio Foundation, Paavo Nurmi Foundation, Finnish Foundation of Cardiovascular Research and Finnish Cultural Foundation, Tampere Tuberculosis Foundation and Emil Aaltonen Foundation.