Graphene field effect nanopore glycine detector

Abstract

We present a new class of Graphene Nanopores that are tunable by means of a lateral in-plane field effect. The field effect is self-induced and does not require an additional gate terminal, and results in strong control over the channel's conductivity. This capability can be used in order to tune the conductivity of the channel, making it comparable to the change in conductance induced by the translocation of a specific biomolecule through the Nanopore, leading to enhanced detection with very high sensitivity and specificity. Here, we present the use of this device for the detection of Glycine, an important biomarker of malignancy in early childhood brain-tumors, whose detection at very low ..