N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease
DJ Wright, T Renoir, ZM Smith, AE Frazier, PS Francis, DR Thorburn, SL McGee, AJ Hannan, LJ Gray
Translational Psychiatry | NATURE PUBLISHING GROUP | Published : 2015
Awarded by Australian Research Council FT3 Future Fellowship
Awarded by National Health and Medical Research Council Career Development Fellowships
Awarded by National Health and Medical Research Council Principal Research Fellowship
Awarded by Australian Research Council Discovery Early Career Research Award
We thank Peter Crouch for his insightful feedback and the Australian Mitochondrial Disease Foundation for partial support of purchasing the Seahorse XF24 Extracellular Flux Analyzer. The Florey Institute of Neuroscience and Mental Health acknowledges the support from the Victorian Government's Operational Infrastructure Support Grant. This work was supported by an Australian Research Council FT3 Future Fellowship (FT100100835) to AJH, National Health and Medical Research Council Career Development Fellowships to SLM (APP1030474) and AEF (APP541920) and a National Health and Medical Research Council Principal Research Fellowship to DRT (APP1022896). DJW holds a University of Melbourne Australian Postgraduate Award. TR is supported by an Australian Research Council Discovery Early Career Research Award (DE140100588).