A Prospective Cohort Study of Antipsychotic Medications in Pregnancy: The First 147 Pregnancies and 100 One Year Old Babies
Jayashri Kulkarni, Roisin Worsley, Heather Gilbert, Emorfia Gavrilidis, Tamsyn E Van Rheenen, Wei Wang, Kay McCauley, Paul Fitzgerald
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2014
BACKGROUND: Many women diagnosed with varying psychiatric disorders take antipsychotic medications during pregnancy. The safety of antipsychotic medications in pregnancy is largely unknown. METHODS: We established the National Register of Antipsychotic Medications in Pregnancy in 2005. Women who are pregnant and taking an antipsychotic medication are interviewed every 6 weeks during pregnancy and then followed until their babies are one year old. The baby's progress is closely followed for the first year of life. FINDINGS: As of April 18 2012, 147 pregnancies had been followed through to completion. There were 142 live births and data is available for 100 one year old babies. 18% of babies w..View full abstract
This study was supported by Australian Rotary Health Research Fund (australianrotaryhealth.com.au; AstraZeneca astrazeneca.com.au); Janssen-Cilag (janssen.com.au); Hospira (hospira.com.au); Eli-Lilly (lilly.com.au). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.