Journal article
Heterogeneity of postpartum depression: a latent class analysis
Karen Putnam, Emma Robertson-Blackmore, Katherine Sharkey, Jennifer Payne, Veerle Bergink, Trine Munk-Olsen, Kristina Deligiannidis, Margaret Altemus, Jeffrey Newport, Gisele Apter, Emmanuel Devouche, Alexander Viktorin, Patrik Magnusson, Paul Lichtenstein, Brenda Penninx, Anne Buist, Justin Bilszta, Michael O'Hara, Scott Stuart, Rebecca Brock Show all
The Lancet Psychiatry | ELSEVIER SCI LTD | Published : 2015
Abstract
BACKGROUND: Maternal depression in the postpartum period confers substantial morbidity and mortality, but the definition of postpartum depression remains controversial. We investigated the heterogeneity of symptoms with the aim of identifying clinical subtypes of postpartum depression. METHODS: Data were aggregated from the international perinatal psychiatry consortium Postpartum Depression: Action Towards Causes and Treatment, which represents 19 institutions in seven countries. 17,912 unique subject records with phenotypic data were submitted. We applied latent class analyses in a two-tiered approach to assess the validity of empirically defined subtypes of postpartum depression. Tier one ..
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Awarded by National Institute of Mental Health
Awarded by ZonMW
Awarded by NIMH
Awarded by NIH
Awarded by French Ministry of Health
Awarded by Geestkracht program of the Netherlands Organisation for Health Research and Development
Awarded by South Carolina Clinical and Translational Research Institute
Awarded by Building Interdisciplinary Research Careers in Women's Health
Awarded by National Institutes for Health
Awarded by Lundbeck Foundation
Awarded by EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
Awarded by NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH
Funding Acknowledgements
The National Institute of Mental Health support SM-B (K23 MH085165-01A1), TM-O, DRR, PFS, and SM-B (1R01MH104468-01), ERB (K23MH080290), and a young investigator award from the Brain & Behavior Research Foundation), KMS (5K23MH086689, JP (K23 MH074799-01A2), VB (FP7-Health-2007 Project no 222963), MWO (MH50524 NIMH), KLW (5R01MH60335, NIMH, 5R01MH071825 NIMH, 5R01MH075921 NIMH, and 5-2R01MH057102), SJR and HT (ZonMW 10.000.1003, NIMH K23 MH097794, and NIH UL1 TR000161), and PJS (ZIA MH002865-09 BEB). KMD is supported by the Worcester Foundation for Biomedical Research. CNE is supported by Pfizer Pharmaceuticals and a young investigator award from the National Alliance for Research on Schizophrenia and Depression. GA and ED are supported by the French Ministry of Health (PHRC 98/001) and Mustela Foundation. BWP is supported by the Geestkracht program of the Netherlands Organisation for Health Research and Development (10-000-1002) and VU University Medical Centre, GGZ Geest, Arkin, Leiden University Medical Centre, GGZ Rivierduinen, University Medical Centre in Groningen, Lentis, GGZ Fries land, GGZ Drenthe, IQ Healthcare, Netherlands Institute for Health Services Research, and Netherlands Institute of Mental Health and Addiction. CG is supported by South Carolina Clinical and Translational Research Institute (UL1 TR000062) & Building Interdisciplinary Research Careers in Women's Health (K12 HD055885). ZNS is supported by the National Institutes for Health (P50 MH-77928 and P50 MH 68036). IJ is supported by the National Centre for Mental Health Wales.