Journal article

Temporal lobe epilepsy caused by mesial temporal sclerosis and temporal neocortical lesions - A clinical and electroencephalographic study of 46 pathologically proven cases

TJ OBrien, C Kilpatrick, V Murrie, S Vogrin, K Morris, MJ Cook

BRAIN | OXFORD UNIV PRESS | Published : 1996


This study aims to determine whether there are important clinico-electrical differences between patients with temporal lobe epilepsy (TLE) secondary to mesial temporal sclerosis (MTS) and those with TLE secondary to a discrete temporal neocortical lesion (NL). The case histories, interictal EEG, seizure semiology, ictal EEG and postoperative outcome of 46 pathologically proven patients (31 MTS and 15 NL) were compared. A history of febrile convulsions (FC) was more common in MTS patients (58% versus 26%, P < 0.05), as was a history of a significant cerebral event at < 4 years of age (22% versus 0%, P < 0.05). There were no statistically significant differences in the incidence or nature of a..

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