The role of circulating 25 hydroxyvitamin D in asthma: a systematic review
R Cassim, MA Russell, CJ Lodge, AJ Lowe, JJ Koplin, SC Dharmage
ALLERGY | WILEY | Published : 2015
Asthma is a major public health issue. The co-occurrence of the high prevalence of asthma and vitamin D deficiency documented globally in recent decades has prompted several investigations into a possible association between the two conditions. The objective of this paper was to synthesize the evidence from studies that have measured the association between serum vitamin D and asthma incidence, prevalence, severity and exacerbations. A systematic search of the literature was performed in PubMed, and the available evidence was summarized both qualitatively and by meta-analysis. Only English language, observational studies measuring serum levels of 25(OH)D as the exposure were included, as thi..View full abstract
AL, CL, JK and SD are supported by the NHMRC.