Circulating vitamin D levels are associated with the presence and severity of coronary artery disease but not peripheral arterial disease in patients undergoing coronary angiography
JY Liew, SR Sasha, PJ Ngu, JL Warren, J Wark, AM Dart, JA Shaw
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | ELSEVIER SCI LTD | Published : 2015
BACKGROUND AND AIMS: To investigate the association between vitamin D levels, angiographic severity of coronary artery disease, arterial stiffness and degree of peripheral arterial disease (PAD) as assessed by ankle brachial index (ABI). METHODS AND RESULTS: 375 patients undergoing coronary angiography from November 2012 to September 2013 were recruited. Serum 25-hydroxyvitamin D (25OHD) levels were measured as were ABI and pulse wave velocity (PWV). Based on the findings of the coronary angiogram, patients were divided into subgroups: Absent, Single, Double and Triple Vessel Disease (as defined by >50% stenosis in each major coronary artery) 0.275 patients not taking vitamin D supplements w..View full abstract
The authors would like to thank Vivian Mak, Jan Jennings and Liz Jenkins for their help with the study. Dr Dart and Shaw are supported by an National Health and Medical Research (NHMRC Australia) program grant and DrWark is supported by an NHMRC project grant.