Journal article

Longitudinal Changes in Microperimetry and Low Luminance Visual Acuity in Age-Related Macular Degeneration

Zhichao Wu, Lauren N Ayton, Chi D Luu, Robyn H Guymer

JAMA Ophthalmology | AMER MEDICAL ASSOC | Published : 2015

Abstract

IMPORTANCE: There is a need for more sensitive measures of disease in intermediate age-related macular degeneration (AMD) to evaluate novel interventions more effectively and expediently. OBJECTIVE: To determine if microperimetry and low luminance visual acuity can detect functional changes over a short duration of follow-up. DESIGN, SETTING, AND PARTICIPANTS: Prospective longitudinal examination of 49 participants with consecutive AMD and 10 healthy participants in a research clinic from May 1, 2012, to December 31, 2013. Forty-one participants had intermediate AMD, 8 had nonfoveal geographic atrophy due to AMD. Participants underwent microperimetry examinations in 1 eye during a 12-month p..

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