Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study
Z Li, YA Wang, W Ledger, DH Edgar, EA Sullivan
HUMAN REPRODUCTION | OXFORD UNIV PRESS | Published : 2014
STUDY QUESTION: What are the clinical efficacy and perinatal outcomes following transfer of vitrified blastocysts compared with transfer of fresh or of slow frozen blastocysts? SUMMARY ANSWER: Compared with slow frozen blastocysts, vitrified blastocysts resulted in significantly higher clinical pregnancy and live delivery rates with similar perinatal outcomes at population level. WHAT IS KNOWN ALREADY: Although vitrification has been reported to be associated with significantly increased post-thaw survival rates compared with slow freezing, there has been a lack of general consensus over which method of cryopreservation (vitrification versus slow freezing) is most appropriate for blastocysts..View full abstract
The Fertility Society of Australia is the funding body for the ANZARD. The authors acknowledge the contribution of Australian and New Zealand fertility clinics in the provision of data to ANZARD.