Journal article

Common Genetic Variation Near Melatonin Receptor MTNR1B Contributes to Raised Plasma Glucose and Increased Risk of Type 2 Diabetes Among Indian Asians and European Caucasians

John C Chambers, Weihua Zhang, Delilah Zabaneh, Joban Sehmi, Piyush Jain, Mark I McCarthy, Philippe Froguel, Aimo Ruokonen, David Balding, Marjo-Riitta Jarvelin, James Scott, Paul Elliott, Jaspal S Kooner


University of Melbourne Researchers


Awarded by British Heart Foundation

Awarded by Wellcome Trust

Awarded by Academy of Finland

Awarded by Medical Research Council

Awarded by National Heart, Lung and Blood Institute

Awarded by Existing Epidemiological Data (STAMPEED) program

Funding Acknowledgements

The LOLIPOP study was supported by the British Heart Foundation (SP/04/002) and the Wellcome Trust. NFBC1966 study was supported by the Academy of Finland (104781), the Medical Research Council (G0500539), University Hospital Oulu, Biocenter, University of Oulu, Finland, National Heart, Lung and Blood Institute Grant 5R01HL087679-02 through the SNP Typing for Association with Multiple Phenotypes from Existing Epidemiological Data (STAMPEED) program (1RL1MH083268-01) and the Wellcome Trust (Project Grant GR069224). The DNA extractions, sample quality control subjects, biobank up-keeping, and aliquotting were performed in the national Public Health Institute, Biomedicum. Helsinki, Finland and supported financially by the Academy of Finland (120315) and Biocentrum Helsinki. For NFBC1966 the wide genotyping was conducted by the Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.r No potential conflicts of interest relevant to this article were reported.r We thank Nelson Freimer, Leena Peltonen, and the research teams involved in LOLIPOP and NFBC1966.