Risk of infection and disease with Mycobacterium tuberculosis among children identified through prospective community-based contact screening in Indonesia
Rina Triasih, Colin Robertson, Trevor Duke, Stephen M Graham
TROPICAL MEDICINE & INTERNATIONAL HEALTH | WILEY | Published : 2015
OBJECTIVE: To identify characteristics of the child contact, index case or environment that are associated with infection or tuberculosis in child contacts in an urban community in Indonesia. METHOD: Children who were close contacts of an index case with pulmonary tuberculosis were screened for infection and disease in Yogyakarta, Indonesia from August 2010 to December 2012. Data of the index case and child were collected prospectively, and all child contacts had clinical assessment, tuberculin skin test (TST) and chest X-ray performed. Those with clinically suspected tuberculosis also had sputum examined by Xpert MTB/RIF and culture. Child contacts were managed according to national guideli..View full abstract
We acknowledge all health staff in the study sites that facilitated recruiting and follow-up of the subjects. This work was supported by AusAID to the Centre for International Child Health and by the TB Operational Research Group, Indonesia.