Vertical Nanowire Electrode Arrays as Novel Electrochemical Label-Free Immunosensors
Babak Nasr, Gursharan Chana, Ting Ting Lee, Nguyen Thanh, Chathurika Abeyrathne, Giovanna M D'Abaco, Mirella Dottori, Efstratios Skafidas
SMALL | WILEY-V C H VERLAG GMBH | Published : 2015
A new method for the fabrication of a label-free electrochemical immunosensor based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP-antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance.