Journal article

What factors influence long-term antidepressant use in primary care? Findings from the Australian diamond cohort study

Gilles Ambresin, Victoria Palmer, Konstancja Densley, Christopher Dowrick, Gail Gilchrist, Jane M Gunn

Journal of Affective Disorders | ELSEVIER | Published : 2015


BACKGROUND: Antidepressants are one of the most commonly prescribed drugs in primary care. The rise in use is mostly due to an increasing number of long-term users of antidepressants (LTU AD). Little is known about the factors driving increased long-term use. We examined the socio-demographic, clinical factors and health service use characteristics associated with LTU AD to extend our understanding of the factors that may be driving the increase in antidepressant use. METHODS: Cross-sectional analysis of 789 participants with probable depression (CES-D≥16) recruited from 30 randomly selected Australian general practices to take part in a ten-year cohort study about depression were surveyed a..

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Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

The diamond study was initiated with pilot funding from the Beyondblue Victorian Centre of Excellence in Depression and Anxiety and the main cohort has received Project Grant funding from the Australian National Health and Medical Research Council (IDs 299869, 454463, 566511 and 1002908). The one year Computer Assisted Tele- phone Interview was funded by a Stream 3 Grant from the Australian Primary Health Care Research Institute (APHCRI). GA was supported by a Research fellowship from the Centre Hospitalier Universitaire Vaudois and the Department of Psychiatry of the University of Lausanne, Switzerland. No funding body had a role in study design; the collection, analysis, and interpretation of data: the writing of the manuscript; or the decision to submit this manuscript for publication.