Journal article

Cost-minimisation analysis of midazolam versus droperidol for acute agitation in the emergency department

EW Chan, JC Knott, D Liew, DMD Taylor, DCM Kong

Journal of Pharmacy Practice and Research | Published : 2012

Abstract

Aim: To compare the costs of midazolam and droperidol for the management of acute agitation in the emergency department (ED). Method: A decision analysis model was used to undertake a cost-minimisation analysis of resource utilisation in the ED of a Melbourne hospital. Data from acutely agitated patients who received midazolam (n = 74) or droperidol (n = 79) in a randomised clinical trial (February 2002 to April 2004) were reviewed. Results: All direct medical and non-medical costs relating to the management of acute agitation in the ED were analysed. The average cost scenario was estimated for the 2 treatments. The model simulated 9 possible outcomes based on whether patients were 'sedated'..

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