Journal article

Adult dyslipidemia prediction is improved by repeated measurements in childhood and young adulthood. The Cardiovascular Risk in Young Finns Study

Joel Nuotio, Mervi Oikonen, Costan G Magnussen, Jorma SA Viikari, Nina Hutri-Kahonen, Antti Jula, Russell Thomson, Matthew A Sabin, Stephen R Daniels, Olli T Raitakari, Markus Juonala

Atherosclerosis | ELSEVIER IRELAND LTD | Published : 2015

Abstract

BACKGROUND: Prediction of adult dyslipidemia has been suggested to improve with multiple measurements in childhood or young adulthood, but there is paucity of specific data from longitudinal studies. METHODS AND RESULTS: The sample comprised 1912 subjects (54% women) from the Cardiovascular Risk in Young Finns Study who had fasting lipid and lipoprotein measurements collected at three time-points in childhood/young adulthood and had at least one follow-up in later adulthood. Childhood/young adult dyslipidemia was defined as total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C) or triglycerides (TG) in the highest quintile, o..

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Grants

Awarded by National Health and Medical Research Council Early Career Fellowship


Funding Acknowledgements

The Young Finns Study has been financially supported by the Academy of Finland, the Social Insurance Institution of Finland, Kuopio, Tampere and Turku University Hospital Medical Funds, Orion-Farmos Research Foundation, Juho Vainio Foundation, Paavo Nurmi Foundation, Finnish Medical Foundation, Maud Kuistila Foundation, Paulo Foundation, Finnish Foundation of Cardiovascular Research, Finnish Cultural Foundation, Sigrid Juselius Foundation, Tampere Tuberculosis Foundation and Emil Aaltonen Foundation. Costan G. Magnussen is supported through a National Health and Medical Research Council Early Career Fellowship (APP1037559).