HIV and aging: Insights from the Asia Pacific HIV Observational Database (APHOD)

N Han; ST Wright; CC O'Connor; J Hoy; S Ponnampalavanar; M Grotowski; HX Zhao; A Kamarulzaman; D Ellis; M Bloch; T Franic; S Agrawal; L McCann; N Cunningham; T Vincent; D Allen; JL Little; D Smith; C Gray; D Baker; R Vale; DJ Templeton; C Dijanosic; E Jackson; K McCallum; S Taylor; D Cooper; A Carr; F Lee; K Hesse; K Sinn; R Norris; R Finlayson; I Prone; J Shakeshaft; K Brown; C McGrath; V McGrath; S Halligan; L Wray; P Read; H Lu; D Couldwell; V Furner; J Watson; C Lawrence; B Mulhall; M Law; K Petoumenos; H McManus; C Bendall; M Boyd; A Kulatunga; P Knibbs; J Chuah; M Ngieng; B Dickson; D Russell; S Downing; D Sowden; J Broom; K Taing; C Johnston; K McGill; D Orth; D Youds; M Kelly; A Gibson; H Magon; W Donohue; R Moore; S Edwards; R Liddle; P Locke; NJ Roth; J Nicolson; H Lau; T Read; J Silvers; W Zeng; K Watson; M Bryant; S Price; I Woolley; M Giles; T Korman; J Williams; D Nolan; J Skett; J Robinson; CV Mean; V Saphonn; K Vohith; FJ Zhang; PCK Li; MP Lee; N Kumarasamy; S Saghayam; C Ezhilarasi; S Pujari

Journal article

HIV and aging: Insights from the Asia Pacific HIV Observational Database (APHOD)

N Han, ST Wright, CC O'Connor, J Hoy, S Ponnampalavanar, M Grotowski, HX Zhao, A Kamarulzaman, D Ellis, M Bloch, T Franic, S Agrawal, L McCann, N Cunningham, T Vincent, D Allen, JL Little, D Smith, C Gray, D Baker Show all

HIV Medicine | Published : 2015

DOI: 10.1111/hiv.12188

Abstract

Objectives: The proportion of people living with HIV/AIDS in the ageing population (>50 years old) is increasing. We aimed to explore the relationship between older age and treatment outcomes in HIV-positive persons from the Asia Pacific region. Methods: Patients from the Australian HIV Observational Database (AHOD) and the TREAT Asia HIV Observational Database (TAHOD) were included in the analysis. We used survival methods to assess the association between older age and all-cause mortality, as well as time to treatment modification. We used regression analyses to evaluate changes in CD4 counts after combination antiretroviral therapy (cART) initiation and determined the odds of detectable v..

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University of Melbourne Researchers

Michelle Giles Author

Grants

Awarded by National Institute of Allergy and Infectious Diseases

Funding Acknowledgements

The TREAT Asia HIV Observational Database and the Australian HIV Observational Database are initiatives of TREAT Asia, a programme of The Foundation for AIDS Research (amfAR), with support from the US National Institutes of Health's National Institute of Allergy and Infectious Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and National Cancer Institute, as part of the International Epidemiologic Databases to Evaluate AIDS (IeDEA; U01AI069907). The Kirby Institute is funded by the Australian Government Department of Health and Ageing, and is affiliated with the Faculty of Medicine, The University of New South Wales. The content of this publication is solely the responsibility of the authors and does not necessarily represent the official views of any of the governments or institutions mentioned above.