Risk charts to identify low and excessive responders among first-cycle IVF/ICSI standard patients

Abstract

Ovarian stimulation carries a risk of either low or excessive ovarian response. The aim was to develop prognostic models for identification of standard (ovulatory and normal basal FSH) patients' risks of low and excessive response to conventional stimulation for IVF/intracytoplasmic sperm injection. Prospectively collected data on 276 first-cycle patients treated with 150 IU recombinant FSH (rFSH)/day in a long agonist protocol were analysed. Logistic regression analysis was applied to the outcome variables: low (seven or less follicles) and excessive (20 or more follicles) response. Variables were woman's age, menstrual cycle length, weight or body mass index, ovarian volume, antral follicl..