Whole genome sequencing in clinical and public health microbiology
JC Kwong, N McCallum, V Sintchenko, BP Howden
PATHOLOGY | ELSEVIER SCIENCE BV | Published : 2015
Genomics and whole genome sequencing (WGS) have the capacity to greatly enhance knowledge and understanding of infectious diseases and clinical microbiology.The growth and availability of bench-top WGS analysers has facilitated the feasibility of genomics in clinical and public health microbiology.Given current resource and infrastructure limitations, WGS is most applicable to use in public health laboratories, reference laboratories, and hospital infection control-affiliated laboratories.As WGS represents the pinnacle for strain characterisation and epidemiological analyses, it is likely to replace traditional typing methods, resistance gene detection and other sequence-based investigations..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC), Australia
Awarded by NHMRC fellowship
JCK is supported by a postgraduate scholarship from the National Health and Medical Research Council (NHMRC), Australia (APP1074824). BPH is supported by a NHMRC fellowship (APP1023526).