Journal article

ULTRASTRUCTURAL EXAMINATION OF THE TARGETS OF SEROTONIN-IMMUNOREACTIVE DESCENDING INTERNEURONS IN THE GUINEA-PIG SMALL-INTESTINE

HM YOUNG, JB FURNESS

JOURNAL OF COMPARATIVE NEUROLOGY | WILEY-LISS | Published : 1995

Abstract

Serotonin neurons are descending interneurons in the myenteric plexus of the guinea pig small intestine. Preembedding single- and double-label immunocytochemistries at the ultrastructural level were used to identify the targets of these serotonin interneurons. Serial ultrathin sections were taken through a myenteric ganglion that had been processed for serotonin immunocytochemistry. The ganglion contained the cell bodies of 69 neurons, including 2 serotonin neurons and 6 neurons with the ultrastructural features of Dogiel type II cells. For each cell body in the ganglion, the number of serotonin inputs (synapses and close contacts) was determined. About 59% of the cell bodies did not receive..

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