Journal article

IDENTIFICATION OF SENSORY NERVE-CELLS IN A PERIPHERAL ORGAN (THE INTESTINE) OF A MAMMAL

WAA KUNZE, JC BORNSTEIN, JB FURNESS

NEUROSCIENCE | PERGAMON-ELSEVIER SCIENCE LTD | Published : 1995

Abstract

It is commonly believed that the cell bodies of mammalian sensory neurons are contained within spinal and cranial sensory ganglia associated with the central nervous system or within the central nervous system itself. However, strong circumstantial evidence implies that some sensory neurons are contained entirely within the gastrointestinal tract. We have investigated this possibility by using intracellular methods to record the responses of myenteric neurons in the guinea-pig small intestine to physiological stimuli applied to the neighbouring mucosa. The results show that the myenteric plexus contains a population of chemosensitive sensory neurons and that these neurons correspond to neuro..

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