CALBINDIN-28 KDA IN ENDOCRINE-CELLS OF KNOWN OR PUTATIVE CALCIUM-REGULATING FUNCTION - THYRO-PARATHYROID C-CELLS, GASTRIC ECL CELLS, INTESTINAL SECRETIN AND ENTEROGLUCAGON CELLS, PANCREATIC GLUCAGON, INSULIN AND PP CELLS, ADRENAL-MEDULLARY NA CELLS AND SOME PITUITARY (TSH QUESTIONABLE) CELLS

Abstract

The distribution of calbindin in some endocrine glands (thyroid, parathyroid, ultimobranchial body, pituitary and adrenals) and in the diffuse endocrine cells of the gut and pancreas has been investigated immunohistochemically using an antiserum raised against the 28 kDa calbindin from chicken duodenum. The identity of calbindin-immunoreactive cells in a number of avian and mammalian species was ascertained by comparison with hormone-reactive cells in consecutive sections or by double immunostaining of the same section with both calbindin and hormone antibodies. Calcitonin-producing C cells of the mammalian and avian thyroid, parathyroid or ultimobranchial body, PP, glucagon and insulin cell..