Journal article
NEURONS WITH 5-HYDROXYTRYPTAMINE-LIKE IMMUNOREACTIVITY IN THE ENTERIC NERVOUS-SYSTEM - THEIR VISUALIZATION AND REACTIONS TO DRUG-TREATMENT
M COSTA, JB FURNESS, AC CUELLO, AAJ VERHOFSTAD, HWJ STEINBUSCH, RP ELDE
NEUROSCIENCE | PERGAMON-ELSEVIER SCIENCE LTD | Published : 1982
Abstract
Immunoreactive nerve cell bodies and fibres in the intestine have been examined using three antibody preparations raised against 5-hydroxytryptamine. Cross reactivity studies indicate that the substance localized was an hydroxylated indoleamine. In the guinea-pig small intestine, nerve cell bodies were located in the myenteric plexus and varicose fibres were found in the ganglia of the myenteric and submucous plexus. The nerve cell bodies had prominent short, broad processes and a single long process. Similar nerve cells and fibres were found in the guinea-pig stomach and large intestine and areas of intestine that were examined in mice, rabbits and rats. Properties of the neurons were exami..
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