Journal article

ULTRASTRUCTURAL ANALYSIS OF SUBSTANCE-P-IMMUNOREACTIVE NERVE-FIBERS IN MYENTERIC GANGLIA OF GUINEA-PIG SMALL-INTESTINE

IJ LLEWELLYNSMITH, JB FURNESS, M COSTA

JOURNAL OF NEUROSCIENCE | SOC NEUROSCIENCE | Published : 1989

Abstract

Electron microscopic immunocytochemistry has been used to study the distribution and synaptic relationships of substance P (SP)-immunoreactive nerve fibers in ultrathin sections from whole-mount preparations of myenteric ganglia from guinea pig small intestine. At the light microscopic level, myenteric ganglia stained for ultrastructural study contained dense arrays of SP-immunoreactive nerve fibers around and between the neuronal and glial cell bodies. At the electron microscopic level, SP-containing nerve fiber profiles occurred throughout the neuropil of the myenteric ganglia. Both vesicle-containing and nonvesiculated nerve fiber profiles were immunoreactive. The positive vesiculated pro..

View full abstract

University of Melbourne Researchers