Journal article

MIGRATION OF THE MYOELECTRIC COMPLEX AFTER INTERRUPTION OF THE MYENTERIC PLEXUS - INTESTINAL TRANSECTION AND REGENERATION OF ENTERIC NERVES IN THE GUINEA-PIG

JJ GALLIGAN, JB FURNESS, M COSTA

GASTROENTEROLOGY | W B SAUNDERS CO | Published : 1989

Abstract

The effects of surgical interruption of the myenteric plexus (myectomy), extrinsic denervation of a length of small intestine, or transection and reanastomosis of the intestinal wall on migration of phase III of the migrating myoelectric complex was studied in guinea pigs. In addition, the recovery of phase III migration and the regrowth of intestinal nerves and muscle across the reanastomosis was studied at various times up to 60 days after surgery. At 6-9 days after surgery, phase III did not migrate past the myectomy during 50%-60% of recorded migrating myoelectric complexes and transection and reanastomosis of the intestinal wall blocked aboral progression of phase III in 90% of cases. E..

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