CORRELATED ELECTROPHYSIOLOGICAL AND HISTOCHEMICAL-STUDIES OF SUBMUCOUS NEURONS AND THEIR CONTRIBUTION TO UNDERSTANDING ENTERIC NEURAL CIRCUITS

Abstract

Neither submucous ganglia, nor intestinal secretomotor reflexes are mentioned in the majority of the textbooks of physiology; because it has been realized only very recently that the submucous neurons may have important influences on whole body water and electrolyte balance. In the present review, we trace the rapid progress that has been made in determining the physiological properties of submucous neurons with known chemistry and projections in the guinea-pig small intestine, and we analyze how the work relates to studies in vivo of the neuronal control of intestinal trans-epithelial fluid transport. Four types of submucous neurons, which appear to be the full complement in the guinea-pig ..